Leptin is also known to have some dramatic effects on the brain, one of them being stopping the progression of Alzheimer’s disease in the early stages. Researchers say that synapses are the first ones to get affected as the most common form of dementia starts to develop, a condition which is also irreversible.
Alzheimer’s disease is a chronic condition that takes years to develop but has no cure.
New Delhi: As per researchers from the University of Dundee, a common hormone produced by the human body could play a crucial role in stopping early-stage Alzheimer’s disease. Leptin is a hormone released by fat cells for appetite regulation. Scientists say that a small part of this could reduce the toxic effects of the two proteins in the brain known as tau and amyloid. The build-up of these proteins contributes to formation of tangles and plaque around brain cells that eventually lead to memory loss and Alzheimer’s disease. However, its signs can take years to appear.
How does leptin affect Alzheimer’s disease risk?
Leptin is also known to have some dramatic effects on the brain, one of them being stopping the progression of Alzheimer’s disease in the early stages. Researchers say that synapses are the first ones to get affected as the most common form of dementia starts to develop, a condition which is also irreversible. Research shows that using leptin could therefore do the trick. Researchers said that leptin could significantly slow down the progression of the disease, even stop it. It was found that applying the homeone can block tau and amyloid from interfering with synapses eventually causing memory loss.
Researchers also discovered six amino acid fragments that could slow down the progression of the disease. This further allowed researchers to come up with a drug template with the leptin fragments. However, they also added that it can take years for such drugs to become available – approximately a decade. Even if the drug is developed, it has to go though several tests and safety checks before being available for use by patients.
What are the symptoms of Alzheimer’s disease?
Alzheimer’s disease is a chronic condition that takes years to develop but has no cure. Overtime, this form of dementia can only be controlled in terms of progression. The symptoms of this disease are:
Difficulty in concentrating
Problems in planning or completing tasks
Inability to perform basic tasks
Difficulty in making conversation
Irritability, anxiousness, feeling low
Doctors say that the following can help reduce Alzheimer’s disease risk:
Regular exercise
Quitting smoking
Limiting alcohol intake
Staying socially and mentally active
Balanced diet
Managing blood pressure, blood sugar, cholesterol
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